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Pathology · Question 4 of 1040%

A blood film from a 28-year-old patient with high fever and rigors shows intraerythrocytic ring forms and banana-shaped gametocytes. Which Plasmodium species is responsible?

AP. vivaxYour answer
BP. falciparum✓ Correct
CP. malariae
DP. ovale
AI ExplanationClaude

P. falciparum is the only species that produces characteristic crescent- or banana-shaped gametocytes. The ring forms are typically small and delicate, often with two chromatin dots. It is the most lethal species due to its ability to infect all ages of RBCs and cause cytoadherence. P. vivax and P. ovaleproduce enlarged, stippled RBCs (Schüffner's dots), while P. malariae produces band forms.

Visuals

Ring forms ×100

Ring forms ×100

Banana gametocyte

Banana gametocyte

Ring stage ×1000

Ring stage ×1000

Pathophysiology

P. falciparum sporozoites
RBC invasion (all stages)
Cytoadherence + rosetting
Cerebral malaria
Severe anaemia

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